This sterone is manufactured
from cholesterol in the tiny energy cells called the mitochondria. Pregnenolone
is the precursor of many steroids and as such is eventually converted into a multitude
of steroids and neurosteroids. Click here to see a figure depicting the relationship
of Pregnenolone in the steroid pathway. As such, pregnenolone supplements can
help improve energy levels and help fight against chronic fatigue. Pregnenolone
was discovered in a 1995 clinical study to be the most potent memory enhancing
sterone discovered to date, possibly 100 times more effective for memory than
DHEA. In animals, pregnenolone levels are clearly related to cognitive performance,
the higher the level, the better the performance. Pregnenolone has been in use
for the treatment of arthritis since the 1940s and although it had fallen
into disuse for that purpose, its safety record and low toxicity is impressive.
Other clinical studies show that pregenenolone is good at reducing stress levels
and inducing a better state of relaxation. As with DHEA, pregnenolone levels decline
with age, dosages vary widely; a broad spectrum of studies would indicate anti-aging
daily doses of 10mg to 30mg (maximum 50mg). Arthritis doses of 100mg to 200mg
and as high as 300mg to 500mg for senile dementia. Pregnenolone can convert into
any number of different metabolites and there isn't at present a surefire way
of ensuring the ones you want and the ones you may not want. As such, it is possible
that some of pregnenolone will convert into DHEA, and either as a result or more
directly into testosterone, (although in our experience pregnenolone is less likely
to convert into testosterone than DHEA). However, testosterone can convert into
the estrogen estradiol, to help prevent this we recommend the use of DIM (Di-indolylmethane)
with regular pregnenolone use.
All Prices are subject to change based on the latest prices from IAS.
"I have MS, but now I have the energy I have the energy
to leave my wheelchair for long periods. Although I am taking a combination of
products including your Idebenone and ATP I feel that its the Pregnenolone that
plays a biggest role in my ability to live a near-normal day, many many thanks
and keep up the good work." B.M.L., Switzerland.